I-10 is also a critical hurricane evacuation route for the Gulf Coast region. Major metropolitan areas along I-10 include Phoenix, AZ, Tucson, AZ, El Paso, TX, San Antonio, TX, Baton Rouge, LA, New Orleans, LA and Mobile, AL. It connects Los Angeles, CA – the nation’s second largest city – with Jacksonville, FL – one of the country’s busiest ports. This interstate is a key route for travel and freight movement in the southern United States.
Jacksonville, FL is the terminus for I-10. Travelers will encounter everything from Los Angeles, CA to Houston, TX. I-10 is the most southernly cross-country highway in the United States. Interstate 10 is the fourth longest interstate in the US, spanning 2,460 miles from Santa Monica, CA to Jacksonville, FL.
Road Trip and Weather Conditions for Interstate I-10